The career of Maclyn McCarty
نویسندگان
چکیده
On January 2, 2005, the scientific community lost a valued colleague and friend. Maclyn McCarty, or "Mac," as he was better known, was perhaps most recognized for his part in the discovery of DNA as the carrier of genetic information. But McCarty's scientific career was long and fruitful, and his contributions to science were vast. This retrospective offers a look at some of Mac's other notable scientific achievements.
منابع مشابه
A Path to Discovery: The Career of Maclyn McCarty
October 2005 | Volume 3 | Issue 10 | e341 Maclyn McCarty, who devoted his life as a physician-scientist to studying infectious disease organisms, was best known for his part in the monumental discovery that DNA, rather than protein, constituted the chemical nature of a gene. Uncovering the molecular secret of the gene in question—that for the capsular polysaccharide of pneumococcal bacteria—led...
متن کاملOBLITUARIES Maclyn McCarty ( 1911 - 2005 )
“If I have seen further, it is by standing on the shoulders of giants” (letter of Isaac Newton to Robert Hooke). This wellknown sentence of Newton finds its correct meaning in biology through the work of Oswald Avery (1877-1955), Colin MacLeod (1909-1972), and Maclyn McCarty (1911-2005) that was published in 1944 in The Journal of Experimental Medicine, which showed that DNA carried genetic inf...
متن کاملPneumococcal Transformation : Genes are Made of DNA Richard
Copyright 2009, American Society for Investigative Pathology 29 The finding that DNA transmits heredity is considered by many to be the most important discovery in biology during the 20th century. Amazingly, the reception given the publication by Avery and colleagues announcing their discovery hardly fit such a fundamental advance. To a surprising degree the publication went unnoticed. The arti...
متن کاملT H E OCCURRENCE OF POLYGLYCEROPHOSPHATE AS AN A N T I G E N I C COMPONENT OF VARIOUS GRAM-POSITIVE BACTERIAL SPECIES BY MACLYN McCARTY, M.D
The present report deals with the identification of a new bacterial substance which was first recognized as a result of its reactivity with certain streptococcal antisera. Extracts of Groups A to G streptococci, as well as those of various other Gram-positive bacteria, give strong precipitin reactions with these antisera, indicating that the substance is widely distributed in the microbial worl...
متن کاملStudies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types
It has been shown that extremely minute amounts of purified preparations of desoxyribonuclease are capable of bringing about the complete and irreversible inactivation of the transforming substance of Pneumococcus Type III. The significance of the effect of the enzyme, and its bearing on the chemical nature of the transforming substance, together with certain considerations concerning the biolo...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 201 شماره
صفحات -
تاریخ انتشار 2005